Odds, spread, Ohio State lines vs. Wisconsin: Week 4 College Football Picks, Predictions

Ohio State and Wisconsin meet in the anticipated Big Ten opening match of both Horseshoe teams in College Football Week 4 action on Saturday.

Ohio State is perfect in three games after an opening win over Notre Dame, while Wisconsin is 2-1 after a shocking loss at home to Washington State two weeks ago.

What do experts think of the matchup? Let’s see how the College Football Power Index computer prediction model designs the game.

Ohio State odds, spread, predictions vs. Wisconsin

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